Cortical stimulation leads to shortened myelin sheaths and increased axonal branching in spared axons after cervical spinal cord injury. Kondiles, B. R., Murphy, R. L., Widman, A. J., Perlmutter, S. I. & Horner, P. J. Aug 2023. In: Glia. 71(8):1947-1959. doi: 10.1002/glia.24376

Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury. Wei, H., Wu, X., Withrow, J., Cuevas-Diaz Duran, R., Singh, S., Chaboub, L. S., Rakshit, J., Mejia, J., Rolfe, A., Herrera, J. J., Horner, P. J. & Wu, J. Q., May 30 2023, In: Cell Reports. 42, 5, 112486. doi: 10.1016/j.celrep.2023.112486

Magnetic resonance-guided stereotaxy for infusions to the pig brain. Cruz-Garza, J. G., Taghlabi, K. M., Bhenderu, L. S., Gupta, S., Pandey, A., Frazier, A. M., Brisbay, S., Patterson, J. D., Salegio, E. A., Kantorak, C. J., Karmonik, C., Horner, P. J., Rostomily, R. C. & Faraji, A. H., Mar 31 2023, In: Journal of visualized experiments : JoVE. 193. doi: 10.3791/64079

Rigor and reproducibility in analysis of rodent behavior utilizing the forelimb reaching task following a cervical spinal cord injury. Salazar, B. H., Hoffman, K. A., Fraizer, A. M., Humes, F., Hogan, M. K., Horner, M. A., Yadegar, T., Trusler, S., Hamilton, G. F. & Horner, P. J., Feb 15 2023, In: Behavioural Brain Research. 439, 114188. doi: 10.1016/j.bbr.2022.114188

Assessing Gq-GPCR–induced human astrocyte reactivity using bioengineered neural organoids. Cvetkovic, C., Patel, R., Shetty, A., Hogan, M. K., Anderson, M., Basu, N., Aghlara-Fotovat, S., Ramesh, S., Sardar, D., Veiseh, O., Ward, M. E., Deneen, B., Horner, P. J. & Krencik, R., Apr 4 2022, In: Journal of Cell Biology. 221, 4, e202107135. doi: 10.1083/jcb.202107135

Modulation of neuroinflammation via selective nanoparticle-mediated drug delivery to activated microglia/macrophages in spinal cord injury. Stigliano, C., Frazier, A. & Horner, P. J., Nov 2022, In: Advanced Therapeutics. 5, 11, 2200083. doi: 10.1002/adtp.202200083

A micro-LED implant and technique for optogenetic stimulation of the rat spinal cord. Mondello, S. E., Pedigo, B. D., Sunshine, M. D., Fischedick, A. E., Horner, P. J. & Moritz, C. T., Jan 2021, In: Experimental Neurology. 335, 113480. doi: 10.1016/j.expneurol.2020.113480

A wireless spinal stimulation system for ventral activation of the rat cervical spinal cord. Hogan, M. K., Barber, S. M., Rao, Z., Kondiles, B. R., Huang, M., Steele, W. J., Yu, C. & Horner, P. J., Dec 2021, In: Scientific Reports. 11, 1, 14900. doi: 10.1038/s41598-021-94047-1

Quantification of myelinated nerve fraction and degeneration in spinal cord neuropil by SHIFT MRI. Wolfe, T., Hoffman, K., Hogan, M. K., Salazar, B., Tang, X., Chaboub, L., Quini, C. C., Lu, Z. L. & Horner, P. J., Apr 2021, In: Journal of Magnetic Resonance Imaging. 53, 4, p. 1162-1174 13 p. doi: 10.1002/jmri.27397

Transcriptome of rat subcortical white matter and spinal cord after spinal injury and cortical stimulation. Kondiles, B. R., Wei, H., Chaboub, L. S., Horner, P. J., Wu, J. Q. & Perlmutter, S. I., Dec 2021, In: Scientific Data. 8, 1, 175. doi: 10.1038/s41597-021-00953-4

Transplantable human motor networks as a neuron-directed strategy for spinal cord injury. Olmsted, Z. T., Stigliano, C., Scimemi, A., Wolfe, T., Cibelli, J., Horner, P. J. & Paluh, J. L., Aug 20 2021, In: iScience. 24, 8, 102827. doi: 10.1016/j.isci.2021.102827

Complications of epidural spinal stimulation: lessons from the past and alternatives for the future. Taccola, G., Barber, S., Horner, P. J., Bazo, H. A. C. & Sayenko, D., Oct 1 2020, In: Spinal Cord. 58, 10, p. 1049-1059 11 p. doi: 10.1038/s41393-020-0505-8

Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery. Olmsted, Z. T., Stigliano, C., Badri, A., Zhang, F., Williams, A., Koffas, M. A. G., Xie, Y., Linhardt, R. J., Cibelli, J., Horner, P. J. & Paluh, J. L., Jul 31 2020, In: Scientific Reports. 10, 1, 12939. doi: 10.1038/s41598-020-69274-7

Neural stimulation and molecular mechanisms of plasticity and regeneration: A review. Hogan, M. K., Hamilton, G. F. & Horner, P. J., Oct 14 2020, In: Frontiers in Cellular Neuroscience. 14, 271. doi: 10.3389/fncel.2020.00271

Selective antagonism of A1 adenosinergic receptors strengthens the neuromodulation of the sensorimotor network during epidural spinal stimulation. Taccola, G., Salazar, B. H., Apicella, R., Hogan, M. K., Horner, P. J. & Sayenko, D.,  Jul 14 2020. Frontiers in Systems Neuroscience. 14, 44. doi: 10.3389/fnsys.2020.00044

Development of a protocol to assess cell internalization and tissue uptake of magnetic nanoparticles by AC Biosusceptometry. Quini, C. C., Próspero, A. G., Kondiles, B. R., Chaboub, L., Hogan, M. K., Baffa, O., Bakuzis, A. F., Horner, P. J. & Miranda, J. R. A., Mar 1 2019, In : Journal of Magnetism and Magnetic Materials. 473, p. 527-533 7 p.

pH-sensitive polymer micelles provide selective and potentiated lytic capacity to venom peptides for effective intracellular delivery. Peeler, D. J., Thai, S. N., Cheng, Y., Horner, P. J., Sellers, D. L. & Pun, S. H., Feb 1 2019, In: Biomaterials. 192, p. 235-244 10 p. doi: 10.1016/j.biomaterials.2018.11.004

Systematic three-dimensional coculture rapidly recapitulates interactions between human neurons and astrocytes. Krencik, R., Seo, K., van Asperen, J. V., Basu, N., Cvetkovic, C., Barlas, S., Chen, R., Ludwig, C., Wang, C., Ward, M. E., Gan, L., Horner, P. J., Rowitch, D. H. & Ullian, E. M. Dec 12 2017, In: Stem Cell Reports. 9, 6, p. 1745-1753 9 p. doi: 10.1016/j.stemcr.2017.10.026

Myelin plasticity, neural activity, and traumatic neural injury. Kondiles, B. R. & Horner, P. J., Feb 1 2018, In: Developmental Neurobiology. 78, 2, p. 108-122 15 p. doi: 10.1002/dneu.22540

Tunable, injectable hydrogels based on peptide-cross-linked, cyclized polymer nanoparticles for neural progenitor cell delivery. Zhao, T., Sellers, D. L., Cheng, Y., Horner, P. J. & Pun, S. H., Sep 11 2017, In: Biomacromolecules. 18, 9, p. 2723-2731 9 p. doi: 10.1021/acs.biomac.7b00510

3D printed vascularized device for subcutaneous transplantation of human islets. Farina, M., Ballerini, A., Fraga, D. W., Nicolov, E., Hogan, M., Demarchi, D., Scaglione, F., Sabek, O. M., Horner, P., Thekkedath, U., Gaber, O. A. & Grattoni, A., Sep 2017, In: Biotechnology Journal. 12, 9, 1700169. doi: 10.1002/biot.201700169

Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression. Nivison, M. P., Ericson, N. G., Green, V. M., Bielas, J. H., Campbell, J. S. & Horner, P. J., Oct 2017, In: Experimental Neurology. 296, p. 49-61 13 p.doi: 10.1016/j.expneurol.2017.07.001

Fabrication of multipoint side-firing optical fiber by laser micro-ablation. Nguyen, H., Arnob, M. M. P., Becker, A. T., Wolfe, J. C., Hogan, M. K., Horner, P. J. & Shih, W. C., May 1 2017, In: Optics Letters. 42, 9, p. 1808-1811 4 p. doi: 10.1364/OL.42.001808

Development of switchable polymers to address the dilemma of stability and cargo release in polycationic nucleic acid carriers. Cheng, Y., Sellers, D. L., Tan, J. K. Y., Peeler, D. J., Horner, P. J. & Pun, S. H., May 1 2017, In: Biomaterials. 127, p. 89-96 8 p. doi: 10.1016/j.biomaterials.2017.02.036

Non-viral nucleic acid delivery strategies to the central nervous system. Tan, J-K. Y., Sellers, D. L., Pham, B., Pun, S. H. & Horner, P. J., 2016, In: Frontiers in Molecular Neuroscience. 9, p. 108. doi: 10.3389/fnmol.2016.00108

Nano-sized sunflower polycations as effective gene transfer vehicles. Cheng, Y., Wei, H., Tan, J. K. Y., Peeler, D. J., Maris, D. O., Sellers, D. L., Horner, P. J. & Pun, S. H., May 25 2016, In: Small. 12, 20, p. 2750-2758 9 p. doi: 10.1002/smll.201502930

Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons. Lasiene, J., Komine, O., Fujimori-Tonou, N., Powers, B., Endo, F., Watanabe, S., Shijie, J., Ravits, J., Horner, P., Misawa, H. & Yamanaka, K., Feb 18 2016, In: Acta Neuropathologica Communications. 4, p. 15 1 p. doi: 10.1186/s40478-016-0286-7

Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration. Sellers, D. L., Bergen, J. M., Johnson, R. N., Back, H., Ravits, J. M., Horner, P. J. & Pun, S. H., Mar 1 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 9, p. 2514-2519 6 p. doi: 10.1073/pnas.1515526113

Microbubbles and ultrasound increase intraventricular polyplex gene transfer to the brain. Tan, J. K. Y., Pham, B., Zong, Y., Perez, C., Maris, D. O., Hemphill, A., Miao, C. H., Matula, T. J., Mourad, P. D., Wei, H., Sellers, D. L., Horner, P. J. & Pun, S. H., Jun 10 2016, In: Journal of Controlled Release. 231, p. 86-93 8 p.. doi: 10.1016/j.jconrel.2016.02.003

Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma. Cooper, M. L., Crish, S. D., Inman, D. M., Horner, P. J. & Calkins, D. J., Dec 2 2015, In: Experimental Eye Research. doi: 10.1016/j.exer.2015.11.016

A cervical hemi-contusion spinal cord injury model for the investigation of novel therapeutics targeting proximal and distal forelimb functional recovery
Mondello, S. E., Sunshine, M. D., Fischedick, A. E., Moritz, C. T. & Horner, P. J., Dec 15 2015, In: Journal of Neurotrauma. 32, 24, p. 1994-2007 14 p. doi: 10.1089/neu.2014.3792

Neural stem cells in the adult subventricular zone oxidize fatty acids to produce energy and support neurogenic activity. Stoll, E. A., Makin, R., Sweet, I. R., Trevelyan, A. J., Miwa, S., Horner, P. J. & Turnbull, D. M., Jul 1 2015, In: STEM CELLS. 33, 7, p. 2306-2319 14 p.doi: 10.1002/stem.2042

Guanidinylated block copolymers for gene transfer: A comparison with amine-based materials for invitro and invivo gene transfer efficiency. Choi, J. L., Tan, J. K. Y., Sellers, D. L., Wei, H., Horner, P. J. & Pun, S. H., Jun 1 2015, In: Biomaterials. 54, p. 87-96 10 p. doi: 10.1016/j.biomaterials.2015.03.008

A functionalized, injectable hydrogel for localized drug delivery with tunable thermosensitivity: synthesis and characterization of physical and toxicological properties. Elias, P. Z., Liu, G. W., Wei, H., Jensen, M. C., Horner, P. J. & Pun, S. H., Jun 28 2015, In: Journal of Controlled Release. 208, p. 76-84 9 p. doi: 10.1016/j.jconrel.2015.03.003

Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve. Coughlin, L., Morrison, R. S., Horner, P. J. & Inman, D. M., 2015, In: Investigative Ophthalmology and Visual Science. 56, 3, p. 1437-1446 10 p. doi: 10.1167/iovs.14-16126

Poly(lactic-co-glycolic) acid microspheres encapsulated in Pluronic F-127 prolong hirudin delivery and improve functional recovery from a demyelination lesion. Sellers, D. L., Kim, T. H., Mount, C. W., Pun, S. H. & Horner, P. J., Oct 2014, In: Biomaterials. 35, 31, p. 8895-8902 8 p. doi: 10.1016/j.biomaterials.2014.06.051